Prilosec is used to treat various acid-related stomach and/or throat (esophagus) problems (e.g., acid reflux or GERD, ulcers, erosive esophagitis, or Zollinger-Ellison Syndrome). It works by blocking acid production in the stomach. Prilosec may be used in combination with antibiotics (e.g., amoxicillin, clarithromycin) to treat certain types of ulcers. Take Prilosec by mouth, usually once [...]